Entry Level Scientist- Viral Clearance

Eurofins US Network • Lancaster, PA • 3h ago

Lancaster, PA, USA

Full-time

Company Description

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organization services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organizations. It also has a rapidly developing presence in highly specialized and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralized and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2024, Eurofins generated total revenues of EUR 6,515 billion, and has been among the best performing stocks in Europe over the past 20 years.

Job Description

Viral Clearance Services:

Background: Bio/pharmaceutical products cannot be marketed or utilized in clinical trials without first establishing that the manufacturing process is capable of removing potential viral contaminants from the finished product. Viral Clearance Services provides assurance to the pharmaceutical industry that the risk is minimal in exposing a customer to a viral contaminated product.

What do we do: The department deliberately introduces virus into client product intermediates and then measures the ability of the process purification step to remove or inactivate that virus. Multiple steps in a client purification process can be assessed to achieve a cumulative clearance value for a purification process. The testing is designed to satisfy requirements established in the ICH Q5A guidelines. Testing is generally looking for presence/absence of virus plaque forming units (PFU) and comparing the amount of virus that was initially in the sample to the amount of virus in the product containing fraction after the purification has been completed. The Log10 difference between initial titer and the product titer is referred to as a Log Reduction Value.

Center of Focus:

Virus plaque assays - team members perform cell culture manipulation and virus sample dilutions to yield results of the purification process.

Client purification process - team members assist client in performing their viral clearance study by spiking client sample intermediates with virus for their performance of their purification step.

Performance of purification processes - team members perform the client purification processes instead of the client being on site to perform them.

Virus stock preparation - team members perform cell culture manipulation and virus stock propagation to create more virus banks and to improve the titer / purity of virus stocks.

Instrumentation and testing techniques: AKTA Chromatography systems, Biological Safety Cabinets, Microscopes, and various Laboratory Equipment (including hotplates, balances, pH meters, shakers, electronic pipettors, water baths, centrifuges). Continuing investments are made to on-board new technologies for new service offerings and to meet client needs.

Additional Responsibilities:

Completing all training in a timely and complete manner; working with an experienced analyst/mentor performing various tasks and analyses of Bio/pharmaceutical ingredients and products; reviewing or preparing standards and samples for analysis and running any equipment or instrumentation independently and/or with guidance; working efficiently; ensuring that the client receives quality data by reviewing laboratory data for accuracy, clarity, and adherence to GMP and/or GLP regulations.

Qualifications

Minimum Qualifications:

Bachelor's degree in biology or related degree concentration and no previous industry laboratory experience required

Ability to work on the US without immediate or potential future sponsorship

Good dexterity

positive attitude

solution driven

good work habits (organized, efficient, careful, safety-conscious, accurate)

sound scientific logic

understanding of instrumentation

demonstration of organizational skills

ability to work with moderate supervision upon training completion on assigned task

ability to handle multitasking

The Ideal Candidate would possess the following skills/qualities:

Cell Culture, Virology, Plaque Assays, TCID50, Virus Production, AKTA, Protein Purification, Viral Filtration, Virus Inactivation, AEX (anion exchange), CEX (Cation exchange). Customer service oriented, detail and quality oriented, confident/effective communicator (verbal and written), works well in a team setting.

Additional Information

Working schedule will be Full-Time, First Shift, M-F 8am-5pm. Candidates currently living within a commutable distance of Lancaster, PA are encouraged to apply. No relocation assistance will be given. 25% travel may be required. This position is NOT remote.

What we Offer:

Excellent full time benefits including comprehensive medical coverage, dental, and vision options

Life and disability insurance

401(k) with company match

Paid vacation and holidays

Eurofins USA BioPharma Services is a Disabled and Veteran Equal Employment Opportunity employer.

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