Engineer III, Downstream Purification

ThermoFisher Scientific • Saint Louis, MO • 5h ago

Work Schedule

Standard (Mon-Fri)

Environmental Conditions

Laboratory Setting, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.)

Job Description

Discover Impactful Work

As a member of the Bioprocessing Collaboration Center (BCC), you will contribute to the development, evaluation, and application of downstream bioprocessing solutions that support robust and scalable biomanufacturing. This role focuses on chromatography-based purification platforms and data-driven process evaluation within a collaborative, customer-facing technical environment.

You will work closely with scientists, engineers, and customers to generate high-quality experimental data, interpret process performance, and communicate insights that support process understanding and implementation across development and manufacturing @contexts.

Location : On-site in St. Louis, MO. Relocation assistance is NOT provided.

Must be legally authorized to work in the United States without sponsorship.

Must be able to pass a comprehensive background check, which includes a drug screening.

A Day in the Life

In this role, you will:

Design and execute downstream experiments supporting purification process evaluation and optimization, with emphasis on chromatography and UF/DF operations.

Develop, optimize, and execute AKTA-based chromatography methods, including creation and modification of UNICORN control and analysis methods.

Evaluate process performance using experimental data to identify trends, sensitivities, and opportunities for improvement.

Support activities related to process scale-up, implementation, and transfer through well-documented experimental execution and data analysis.

Troubleshoot downstream unit operations, equipment, and workflows, applying sound engineering and scientific principles.

Prepare technical documentation including experimental plans, protocols, reports, and presentations.

Communicate experimental results and technical recommendations clearly to multidisciplinary internal teams and external customers.

Contribute to evaluation and demonstration of Thermo Fisher technologies within the Bioprocessing Collaboration Center.

How Will You Get Here

Education & Experience

Bachelor's degree in Chemical Engineering, Biochemistry, Biomedical Engineering, or a related field; Master's or PhD preferred

Bachelor's degree with 5+ years of relevant industry experience

Master's degree or PhD with 1-2+ years of relevant industry experience

Relevant experience includes downstream bioprocessing, purification development, bioprocess engineering, or manufacturing support in biopharmaceutical environments.

Knowledge, Skills, and Abilities

Required :

Strong hands-on experience with downstream purification operations, including:

Column chromatography (e.g., Protein A, ion exchange, hydrophobic interaction)

Ultrafiltration/diafiltration

Extensive experience working with AKTA chromatography systems and UNICORN software (method development, execution, and data analysis).

Solid understanding of downstream process principles and the ability to interpret purification performance and process trends.

Ability to analyze and summarize experimental data using appropriate statistical and scientific approaches.

Strong written, verbal, and presentation skills, with the ability to communicate effectively to both technical and non-technical audiences.

Excellent organizational and time-management skills, with the ability to manage multiple activities in a dynamic, matrixed environment.

High attention to detail and commitment to quality, data integrity, and standard procedures.

Preferred / Strong Plus:

Working knowledge or experience applying mechanistic modeling, data-driven modeling, or machine learning approaches to bioprocess analysis or optimization.

Familiarity with DOE-based study design and multivariate data analysis.

Exposure to process scale-up, implementation, or technology transfer activities.

Experience supporting technical discussions with external customers.

Physical Requirements

Ability to work in a laboratory environment, including standing for extended periods and performing routine laboratory tasks.

What Sets This Opportunity Apart

Join a globally renowned company at the forefront of scientific innovation.

Collaborate with a team of ambitious professionals who are passionate about making a difference.

Contribute to the success of a company that is dedicated to improving human health and well-being.

Work in a dynamic and fast-paced environment where your skills and contributions will be valued.

Access opportunities for professional growth and development within the organization.

At Thermo Fisher Scientific Inc., we are committed to fostering an inclusive and diverse workplace. We are an equal opportunity employer and value the strengths and perspectives that each individual brings to our team. We strive to provide reasonable accommodations and adjustments to applicants and employees with disabilities to ensure equal access to employment opportunities. If you require any accommodations or adjustments during the application process or throughout your employment, please let us know.

Join our exceptional team and take the next step in your career as an executive assistant at Thermo Fisher Scientific Inc. Apply now and seize this remarkable opportunity to contribute to our mission of enabling our customers to make the world healthier, cleaner, and safer.

Apply today! http://jobs.thermofisher.com

Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status.

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