Senior Scientist - Neuro Oncology (Multiplex IF / Spatial Biology)
Kelly® Science & Clinical
Location: Gaithersburg, MD (Onsite)
Pay Rate: $70-75/hour
Assignment Type: Contract (1-3 months TBD, maternity leave coverage with potential extension)
Start Date: ASAP
Kelly Science & Clinical is seeking a Senior Scientist to support our client's Discovery Oncology team in Gaithersburg, MD. This is a high-impact opportunity to contribute to cutting-edge neuro-oncology research , specifically advancing multiplex immunofluorescence (mIF) panel development and biomarker validation.
This role offers strong visibility and the chance to work alongside a Boston-based neuro-oncology team, with potential for longer-term extension based on performance and project needs.
Position Overview
As a Senior Scientist within the Target Validation group , you will play a key role in supporting early-stage oncology drug development by developing and optimizing multiplex IF assays and validating biomarkers in brain tumor samples. This is not a routine lab role-this position focuses on scientific ownership, problem-solving, and assay development within a specialized indication.
Key Responsibilities
Develop and optimize multiplex immunofluorescence (mIF) assays for neuro-oncology applications
Validate and evaluate up to 13 biomarkers across brain tumor tissue samples
Perform immunofluorescence (IF) on FFPE tissues, including staining, optimization, and QC
Conduct image analysis using platforms such as Halo, QuPath, or ImageJ
Support tissue processing, slide preparation , and histological workflows
Collaborate with cross-functional teams, including a Boston-based neuro-oncology group
Present findings, provide updates, and contribute to scientific discussions
Troubleshoot assay challenges and drive data quality improvements
Required Qualifications
Ph.D. in a relevant scientific discipline
8+ years of research experience in oncology, immunology, or related field
Hands-on experience with immunofluorescence (IF) in FFPE tissues
Strong proficiency with image analysis tools (e.g., Halo, Visiopharm, QuPath, ImageJ)
Experience developing, optimizing, and validating IHC/IF assays
Strong organizational skills and ability to work independently in a fast-paced environment
Preferred Qualifications
Experience in neuro-oncology or neural tissue biology
Background in multiplex IF platforms (e.g., Akoya/Phenoptics, CODEX, GeoMx, CosMx)
Experience with slide preparation and histology workflows
Familiarity with biomarker development and spatial biology
Industry experience in biotech or pharma
Why This Role?
Work on a high-priority neuro-oncology initiative with real impact on drug development
Gain hands-on experience with advanced multiplex and spatial biology technologies
Collaborate with leading scientists in a top-tier global biopharma company
Opportunity for contract extension based on project needs and performance
Competitive compensation for a short-term, high-impact engagement
Apply today to join Kelly Science & Clinical and contribute to our client's mission to transform cancer treatment through innovative science.
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Why Kelly ® Science & Clinical?
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