Analytical Development Scientist (ADCs)

Kelly Services • Devens, MA • 3h ago

Kelly Science & Clinical is seeking Analytical Development Scientist (Antibody Drug Conjugates) to join a growing company located in Devens, MA.

Salary: $100,000-130,000/year

Employment Type: Full Time; Direct Hire

Relocation Assistance available for qualifying candidates

Job Responsibilities:

Execute technical leadership in the planning and analysis of experiments for method development, validation, and product characterization in alignment with ICH guidelines.

Develop, validate and optimize LCMS methods for the qualitative and quantitative analysis of Antibody Drug Conjugates (ADCs), specifically focusing on:

Drug-to-Antibody Ratio (DAR) determination.

Payload quantification for both free and conjugated forms.

Linker stability and degradation profiling.

Site-specific conjugation analysis.

Perform intact mass analysis, peptide mapping, drug-to-antibody ratio (DAR) determination, and payload identification.

Characterize Antibody Drug Conjugates (ADCs) for critical quality attributes including conjugation sites, linker stability, and degradation products.

Support cGMP manufacturing through in-process and release sample analysis.

Author documentation, including test methods, protocols, and regulatory filings.

Maintain LCMS systems (Orbitrap, Q-TOF, Triple Quad) and lead troubleshooting efforts.

Enforce safety and quality standards across all laboratory activities.

Communicate findings to internal teams, clients, and regulatory bodies.

Partner cross-functionally with Chemistry, QC, and Regulatory teams for project delivery.

Mentor scientific staff to foster technical growth and knowledge sharing.

Lead project priorities using strong organizational and leadership skills.

Qualifications:

Master's degree or PhD in Analytical Chemistry, Biochemistry, Chemical/Biomedical Engineering or a related scientific field.

4+ years of hands-on industry experience in analytical method development, validation and characterization of bioconjugates and utilizing LCMS instrumentation for analyzing biologics, preferably Antibody Drug Conjugates (ADCs).

Preferred qualification: Experienced with CE-SDS, HIC, SEC, UV-Vis, fluorescence assays, and immunoassays (ELISA, ECL) for Antibody Drug Conjugate (ADC) analysis, including purity, DAR profiling, aggregation, payload quantification, and antibody detection.

Interested? Please apply today for immediate consideration!

As part of our promise to talent, Kelly supports those who work with us through a variety of benefits, perks, and work-related resources. Kelly offers eligible employees voluntary benefit plans including medical, dental, vision, telemedicine, term life, whole life, accident insurance, critical illness, a legal plan, and short-term disability. As a Kelly employee, you will have access to a retirement savings plan, service bonus and holiday pay plans (earn up to eight paid holidays per benefit year), and a transit spending account. In addition, employees are entitled to earn paid sick leave under the applicable state or local plan. Click here (https://www.mykelly.com/help-support-working-with-kelly-us/#Benefits) for more information on benefits and perks that may be available to you as a member of the Kelly Talent Community.

Why Kelly ® Science & Clinical?

Kelly Science & Clinical is your connection to premier scientific and clinical companies looking to hire industry experts just like you. Our team creates expert talent solutions to solve the world's most critical challenges. Every day, we match science professionals with dream jobs that fit their skills, interests, and career goals-it's the way we think job searching should be. Nearly 100 percent of our science recruiters have a professional background and education in science, so we know a thing or two about the science market and how to get your expertise noticed.

About Kelly

Work changes everything. And at Kelly, we're obsessed with where it can take you. To us, it's about more than simply accepting your next job opportunity. It's the fuel that powers every next step of your life. It's the ripple effect that changes and improves everything for your family, your community, and the world. Which is why, here at Kelly, we are dedicated to providing you with limitless opportunities to enrich your life-just ask the 300,000 people we employ each year.

Kelly is committed to providing equal employment opportunities to all qualified employees and applicants regardless of race, color, sex, sexual orientation, gender identity, religion, national origin, disability, veteran status, age, marital status, pregnancy, genetic information, or any other legally protected status, and we take affirmative action to recruit, employ, and advance qualified individuals with disabilities and protected veterans in the workforce. Requests for accommodation related to our application process can be directed to the Kelly Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment. Kelly participates in E-Verify and will provide the federal government with your Form I-9 information to confirm that you are authorized to work in the U.S.

Kelly Services is proud to be an Equal Employment Opportunity and Affirmative Action employer. We welcome, value, and embrace diversity at all levels and are committed to building a team that is inclusive of a variety of backgrounds, communities, perspectives, and abilities. At Kelly, we believe that the more inclusive we are, the better services we can provide. Requests for accommodation related to our application process can be directed to Kelly's Human Resource Knowledge Center. Kelly complies with the requirements of California's state and local Fair Chance laws. A conviction does not automatically bar individuals from employment.

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