2026 Summer Intern - Synthetic Molecule Process Chemistry

Genentech • South San Francisco, CA • 6h ago

The Position

Department Summary

Synthetic Molecule Process Chemistry at Genentech translates innovative drug candidates from discovery into safe, robust, and scalable Active Pharmaceutical Ingredient (API) manufacturing processes that enable clinical development. Scientists lead from the bench within cross-functional teams, developing enabling chemistry, selecting synthetic routes, and optimizing chemical processes through early-phase GMP manufacture. The role blends scientific creativity with practical execution across process design, safety, sustainability, and supply-chain strategy, in close partnership with internal CMC functions and external collaborators to advance Genentech's pipeline. Speed is essential in early-stage process development; accordingly, the department leverages computational chemistry, machine learning, and robotics to accelerate the development cycle.

This internship position is located in South San Francisco, on-site.

The Opportunity

The successful candidate will use cheminformatics tools to parameterize a set of ionizable lipids for lipid nanoparticles (LNP).

They will use these parameters to develop machine learning models to predict the encapsulation efficiency, immune response, and in vivo distribution of LNPs.

Using these models they will generate recommendations for new ionizable lipids and other components to refine the LNP delivery system.

In collaboration with Synthetic Molecule Pharmaceutics (Formulations / Solid State), they will engage in multiple rounds of optimization, demonstrating lab in the loop optimization for LNPs.

Using python libraries, the intern will develop visualizations to communicate their results.

Program Highlights

Intensive 12-weeks, full-time (40 hours per week) paid internship.

Program start dates are in May/June 2026.

A stipend, based on location, will be provided to help alleviate costs associated with the internship.

Ownership of challenging and impactful business-critical projects.

Work with some of the most talented people in the biotechnology industry.

Who You Are

Required Education:

You meet one of the following criteria:

Must be pursuing or have attained an Associate's Degree.

Must be pursuing a Bachelor's Degree (enrolled student).

Must be pursuing a Master's Degree (enrolled student).

Must be pursuing a PhD (enrolled student).

Required Majors: Chemistry, Biology, Computer Science.

Required Skills:

Candidate must have a background in chemistry or biology, including coursework in organic chemistry.

Candidate must have familiarity with python programming, preferably should be familiar with the standard scientific python stack (numpy, scipy, scikit-learn) including hands-on experience with machine learning methods.

Preferred Knowledge, Skills, and Qualifications

Excellent communication, collaboration, and interpersonal skills.

Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Familiarity with cheminformatics tools such as RDKit or OpenBabel.

Experience with building interactive visualizations in python.

Familiarity with Jupyter Notebooks.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $45.00-$50.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .

Similar Jobs

Senior AI/Machine Learning & Data Platform SW Product Manager

HP Inc. • Palo Alto, CA • 4min ago

Management & Administrative

Senior AI/ML & SW Product Manager to lead the strategy, development, and launch of HP's AI/ML and Data Platforms. This PM will be responsible for translating complex customer and business needs into clear product req...

4min ago

Go to Apply

Software Engineer II - Delivery Search

Uber • San Francisco, CA • 5min ago

Retail & Hospitality

About the Role We are seeking talented Senior Software Engineers to join our Engineering team, supporting Search Engineering efforts. In this role, you will play a key part in designing and optimizing backend infrastruct...

5min ago

Go to Apply

Sr Executive Assistant II

The Walt Disney Company • San Francisco, CA • 5min ago

Disney Entertainment & ESPN Technology Technology is at the heart of Disney's past, present, and future. Disney Entertainment and ESPN Product & Technology is a global organization of engineers, product developer...

5min ago

Go to Apply

Data Scientist Economist

The Hartford • San Francisco, CA • 7min ago

IT & Engineering

Economist - UZ07BE We're determined to make a difference and are proud to be an insurance company that goes well beyond coverages and policies. Working here means having every opportunity to achieve your goals - and to h...

7min ago

Go to Apply

AI & GenAI Data Scientist - Senior Manager

PwC • San Francisco, CA • 9min ago

Management & Administrative

Specialty/Competency: Data, Analytics & AI Industry/Sector: Not Applicable Time Type: Full time Travel Requirements: Up to 80% At PwC, our people in data and analytics focus on leveraging data to drive insights and m...

9min ago

Go to Apply

Product Manager: Capital One Shopping (Remote-Eligible)

Capital One • San Francisco, CA • 11min ago

Management & Administrative

Product Manager: Capital One Shopping (Remote-Eligible) We are looking for a Product Manager to join our growing team in Capital One Shopping. If you have a remarkable ability to use data to tell a story, form a hypothes...

11min ago

Go to Apply

Data Product Lead, YouTube

Google • San Bruno, CA • 14min ago

IT & Engineering

Data Product Lead, YouTube corporatefare_ YouTube place Mountain View, CA, USA; New York, NY, USA; +2 more; +1 more Advanced Experience owning outcomes and decision making, solving ambiguous problems and influencing stak...

14min ago

Go to Apply

Asset Management Operations Manager

Meta • Menlo Park, CA • 1h ago

Management & Administrative

Summary: Meta is seeking an experienced Asset Management Operations Manager to support critical activities and asset lifecycle management of infrastructure hardware including data centers, points-of-presence, integrators...

1h ago

Go to Apply

Medical Assistant

Kaiser Permanente • San Mateo, CA • 1h ago

Hospital & Medical

Job Summary: Assists in examination and treatment of patients under the direction of the Physician and/or Designee. Essential Responsibilities: Interviews patients and measure vital signs and other pertinent information...

1h ago

Go to Apply

Private Bank Internship 2026

Citizens • San Francisco, CA • 2h ago

Finance, Accounting & Banking

Description ???? Start Date:?May 26, 2026 Location: San Francisco CA, Menlo Park CA, New York NY or Boston MA Private Bank Internship Program 2026 Join Citizens Private Bank as a Private Bank Intern and gain hands-on exp...

2h ago

Go to Apply

Subscribe to get new jobs sent directly to you
(no charge, cancel anytime)

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.