Use Your Power for Purpose

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.

What You Will Achieve

Deliver results in a fast-paced matrix-oriented setting, be a contributor to key process purification steps and hold responsibility for various downstream process development activities. This advertised role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, therapeutic proteins, and polysaccharides in commercial operations and late-stage clinical development. The candidate will work across downstream purification functions, projects, and global sites.

In this role, you will:

The MSAT downstream purification group is responsible for providing support to the upstream team, as well as downstream development purification/optimization, mRNA drug substance process activities and providing support to routine manufacturing operations

Candidate should have in-depth scientific knowledge and experience in a wide array of techniques such as mRNA Drug Substance process, UF/DF, Column Chromatograph, and well versed with standard downstream equipment, e.g. AKTAs

Development and qualification of purification techniques.

Ensure the proper and timely execution in all aspects of purification processing to support group activities

Perform scale-down purifications of biologics including enzymes using precipitation, depth filtration, ultrafiltration and chromatography with minimal assistance of lab supervisor/designee

Qualified candidates will serve as a purification and biochemistry resource for the department and project teams, while proactively keeping historical product knowledge and experience.

Ensures effective, high-quality, timely and appropriate documentation in electronic laboratory notebooks and internal technical reports; presents data/ strategy to scientists and management in appropriate internal and external venues (technical meetings, project team meetings, conferences) as appropriate.

Contributes to safe, efficient, effective and harmonious lab environment, ensures appropriate cleanliness and status/ operability of shared or assigned lab space or equipment; strong lab citizen and collaborative team player; approaches the job with energy and commitment; frequently demonstrates initiative.

Participate in multi-disciplinary teams to resolve complex issues - Assist in manufacturing investigations and process troubleshooting - Assist on process improvement projects

Participate and lead organizational initiatives aligning to Six Sigma practices

Here Is What You Need (Minimum Requirements)

Applicant must have a Bachelor's degree with at least 2 years of experience; OR a master's degree with +1 year of experience; OR an associate's degree with 6 years of experience; OR a high school diploma (or equivalent) and 8 years of relevant experience

Previous experience with interdisciplinary drug development teams and industrial experience developing purification strategies and methods in support of product and process development and to assess the quality and characteristics of biotherapeutics.

Demonstrated technical writing skills

Experience with technologies focused on mRNA drug substance process such as In-vitro transcription reactions, Enzyme based process and purification of biomolecules such as, Enzymatic reactions, AKTA, UF/DF, Column Chromatography

Bonus Points If You Have (Preferred Requirements)

Knowledge and experience in Critical Quality Attributes (CQA) principles and practices and product specifications and specification setting.

Demonstrated technical skills and scientific expertise in purification process development and troubleshooting

Familiarity with mRNA Lipid nano particle formulation and Final Drug Product (FDP) processes

Experience with Microsoft Office, Excel, Word, etc.

Curiosity about seeking and applying current relevant scientific literature.

Physical/Mental Requirements

Demonstrated effective communication are strongly desired.

Change agile, functional in a fast-paced team environment where multi-tasking required.

Enthusiastic about communicating to a broad range of stakeholders (from novices to experts) and seeking agreement in complex situations.

Non-Standard Work Schedule, Travel, or Environment Requirements

Schedule is primarily Monday through Friday, 1st shift.

Other Job Details:

Last day to Apply: July 10th

Eligible for Relocation Assistance: No

Work Location Assignment: On Premise

The annual base salary for this position ranges from $80 300,00 to $133 900,00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 10,0% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and/or eligibility.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the @type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.

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