Sr. Scientist - Cardiometabolic Research

Amgen • South San Francisco, CA • 13h ago

Join Amgen's Mission of Serving Patients

At Amgen, if you feel like you're part of something bigger, it's because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.

Since 1980, we've helped pioneer the world of biotech in our fight against the world's toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you'll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you'll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Sr. Scientist - Cardiometabolic Research

What you will do

Let's do this. Let's change the world. In this vital role you will be at the forefront of ground breaking research, our Cardiometabolic Therapeutic Area team is dedicated to understanding the complexities of disease biology and discovering novel therapeutics. You'll collaborate with a team of world-class scientists, leveraging state-of-the-art technologies to make a real impact on patients' lives.

As a Senior Scientist, you will:

Design and perform laboratory-based assays to deepen our understanding of cardiometabolic disease biology

Develop functional screening assays and evaluate potential therapeutics to advance the pre-clinical pipeline

Organize and interpret data and present work to colleagues and project teams

Contribute to the identification and validation of therapeutic targets

Coordinate cross-functional efforts to achieve project goals and drive project advancement

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. We are seeking a highly motivated scientist with excellent communication skills with the following qualifications:

Basic Qualifications:

Doctorate Degree (PhD) or

Master's Degree with 3 years of experience or

Bachelor's Degree with 5 years of experience.

Preferred Qualifications:

Demonstrated expertise in the molecular mechanisms underlying cardiovascular disease biology. The successful candidate will have a strong record of high-impact publications in this field.

Extensive experience in high-throughput cell-based and biochemical assays, including live cell imaging and image processing, qPCR, ddPCR, Western Blot, MSD, ELISA and flow-based expression analysis

Hands-on expertise with cell line engineering technologies, including CRISPR and lentivirus, retrovirus-, or piggyBac-based stable cell line generation

Experience with high-throughput functional perturbation approaches, including CRISPR-based or RNAi screens

Experience with single-cell transcriptomics or other omics data for disease pathology and novel target identification

What you can expect from us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:

A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts

A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan

Stock-based long-term incentives

Award-winning time-off plans

Flexible work models, including remote and hybrid work arrangements, where possible

Apply now and make a lasting impact with the Amgen team.

careers.amgen.com

In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Application deadline

Amgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.

We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation. Amgen is an Equal Opportunity employer and will consider you without regard to your race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

Amgen

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