Associate Principal Scientist, Gene Editing and Biologics Research

Insmed Inc. • Bridgewater, NJ • 2d ago

At Insmed, every moment and every patient counts - and so does every person who joins in. As a global biopharmaceutical company dedicated to transforming the lives of patients with serious and rare diseases, you'll be part of a community that prioritizes the human experience, celebrates curiosity, and values every person's contributions to meaningful progress. That commitment has earned us recognition as Science magazine's No. 1 Top Employer for four consecutive years, certification as a Great Place to Work in the U.S., and a place on The Sunday Times Best Places to Work list in the UK.For patients, for each other, and for the future of science, we're in. Are you?About the Role:We are seeking a highly motivated, creative, and passionate Associate Principal Scientist to lead discovery and development campaigns focused on next-generation biotherapies and gene editing technologies.The candidate will work within a multidisciplinary team focused on the design, engineering, characterization, formulation development, and translational pharmacology models of ground-breaking biotherapeutics.What You'll Do: Drive biomolecular engineering and pharmacology efforts within Insmed research projects, including strategy and methods development Handle, mentor, and develop a team of project scientists focused on protein engineering and next-generation gene editing technologies Conceptualize, construct, validate, and implement high throughput screening platforms to enable candidate selection from large panels and/or combinatorial libraries of engineered protein variants Develop, validate, and deploy functional and pharmacological assays to characterize protein performance in vitro and in vivo Establish and handle partnerships with research teams from computational biology, immunology, bioanalytical, in vivo, and formulation science Establish and handle partnerships with cross functional team members from DMPK, toxicology, translational bioanalytics, technical operations, and program management Maintain accurate, detailed, and timely records of methods development, experimental data, and data analysis in an electronic notebook system and technical reports Perform data review to ensure accuracy, completeness, and validity Present scientific results to the larger Insmed research group and external scientific community, as needed Assist with coordination and day-to-day management of site operationsWho You Are: Requires a minimum of a PhD and 9+ years of experience in molecular and cellular biology, bioengineering, biochemistry, immunology, microbiology, or related field Must have demonstrated management and leadership experience Deep expertise in therapeutic gene editing required Requires mastery of applied molecular and cellular biology, protein biochemistry, recombinant DNA technology, protein mutagenesis, and high throughput library screening Experience with translational in vivo models of genetic disease and therapeutic gene therapy/editing required Excellent communication (verbal and written) and problem-solving skills required Highly organized with attention to detail, clarity, accuracy, and concisenessPay Range:$127,000.00-178,533.00 AnnualLife at InsmedAt Insmed, you'll find a culture as human as our mission-intentionally designed for the people behind it. You deserve a workplace that reflects the same care you bring to your work each day, with support for how you work, how you grow, and how you show up for patients, your team, and yourself.Highlights of our U.S. offerings include: Comprehensive medical, dental, and vision coverage and mental health support, annual wellbeing reimbursement, and access to our Employee Assistance Program (EAP) Generous paid time off policies, fertility and family-forming benefits, caregiver support, and flexible work schedules with purposeful in-person collaboration 401(k) plan with a competitive company match, annual equity awards, and participation in our Employee Stock

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