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Downstream Associate Scientist

System One • Seattle, WA • 18h ago

Job Title: Downstream Associate Scientist

Location: Seattle, WA

Hours/Schedule: M-F; Standard Business Hours

Compensation: $46.38 - $58.90/hr

Type: Contract

Responsibilities

Design, execute, and troubleshoot downstream development experiments supporting next-generation lentiviral vector production

Identify, onboard, and develop novel downstream technologies in collaboration with internal and external partners

Provide experimental design and executional support to team members

Support cross-functional development efforts e.g. downstream process development, high-throughput process development

Perform hands-on experimental work in the early-phase development and optimization of primarily downstream (clarification, chromatography, tangential and normal flow filtration) unit operations for viral vector production

Work independently and within teams to design, execute, and analyze experiments

Maintain accurate and detailed laboratory notebook and documentation

Summarize and present data in group meetings and contribute to group discussions and team strategy

Author technical reports and study memos

Requirements

B.S. with 2+ years of experience or M.S. with 0-2 years of hands-on downstream experience

Experience with Akta Avant chromatography systems and Unicorn software

Experience with automated and semi-automated filtration systems (Pendotech, Repligen KR2i, Ambr Crossflow, etc)

Hands-on process development experience

Independently motivated with ability to multi-task, problem-solve, and coordinate activities within a team

Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)

Preferred Qualifications:

Degree in biological or chemical engineering, biochemistry, or bio-related field

Experience in the development of viral vectors (e.g. adeno-, retro-, lenti-), including successful transfer for GMP manufacturing

Experience with single-use technologies

Benefits

System One offers eligible employees health and welfare benefits coverage options, including medical, dental, vision, spending accounts, life insurance, voluntary plans, and participation in a 401(k) plan.

Ref: #558-Scientific

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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