At Johnson & Johnson,?we believe health is everything. Our strength in healthcare innovation empowers us to build a?world where complex diseases are prevented, treated, and cured,?where treatments are smarter and less invasive, and?solutions are personal.?Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity.?Learn more at https://www.jnj.com
Job Function:
Discovery & Pre-Clinical/Clinical Development
Job Sub Function:
Translational Discovery & Development Biomarkers
Job Category:
Scientific/Technology
All Job Posting Locations:
Spring House, Pennsylvania, United States of America
Job Description:
About Innovative Medicine
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine
About Immunology
Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.
Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.
Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.
We are searching for the best talent for a Principal Scientist, Translational Science Immunology to be located in Spring House, Pennsylvania.
As Immunology Leaders, we know immunology is vital to human health. Driven by a relentless focus on patient unmet needs, we will redefine treatments for immune diseases by delivering transformational and accessible therapies and regimens to patients with immune-mediated disease. For more than two decades we have been a world leader in the development of transformational medicines, establishing one of the strongest, first-in-class portfolios and pipelines in the industry, including the first tumor necrosis factor (TNF) inhibitor, and first interleukin (IL)-12 and IL-23 inhibitors. We tirelessly push the boundaries of science and creativity, applying our deep disease insights, novel pathway science, new technologies, and treatment modalities to restore immune homeostasis.
The Translational Science group (TS) has the primary responsibility for creating and implementing innovative translational plans for portfolio assets. TS is a group within the Immunology Therapeutic Area consisting of a Translational Science and Translational Medicine (TM) teams that form the Translational Science and Medicine department (TSM). TS has combined expertise in developing asset specific and disease specific biomarkers from conception, assay development and implementation into clinical studies to study and drive biological understanding of immunologic disease and immunologic pathways. Organizationally, TSM serves as a pivotal bridge between Discovery Research and the later phase Clinical Development group. TSM provides the necessary scientific and clinical expertise to advance an industry-leading pipeline of
novel mechanism small molecules and biologic agents to address unmet need in immune-mediated diseases.
This position is within the Immunology Translational Sciences group and requires a highly motivated and skilled candidate to drive the translational research of innovative therapies across immune-mediated diseases. The Principal Scientist will provide biomarker support for Immunology clinical programs with a focus on maternal fetal immunology and rare diseases. The successful candidate will lead a matrixed team with diverse expertise in assay development and translational research. Key activities include leading biomarker discovery efforts, assay development and assay validation (including but not limited to flow cytometry assays), organizational excellence, and laboratory supervision. The successful candidate will utilize a full suite of advanced technologies to enable cutting edge research. Furthermore, the candidate will partner with cross-functional teams to engage in interactions with external experts, commercial vendors, and academic institutions to advance Immunology portfolio
Primary responsibilities:
Drive operational efficiency for translational biomarker implementation, including engagement with external vendors and academic partners
Coordinate experiments with other scientists across functional groups and external partners to manage multiple projects and to present results to internal stakeholders while adhering to aggressive timelines
Guide team members in high quality biomarker data generation and applying those results to making strategic decisions
Proactively investigate and provide improvements to processes across the team
Prepare and/or direct the preparation and review of protocols, ICF, clinical study reports and translational science sections of Translational plans, IBs, INDs, abstracts, manuscripts, and technical reports
Deliver on study milestones and commitments
Contribute to the strategies on molecular understanding of human diseases, patient stratification and biomarker-based endpoint translational strategies
Contribute to the overall department's strategic direction with special focus on increasing the impact of translational science approaches in drug discovery and development
Lead internal and external collaborations to increase team capabilities or address a strategic need
Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution
Help build an extensive external network of leaders in Immunology to enable strategic partnerships and awareness of advances in translational and biomarker research
Foster a collaborative, creative, and rigorous culture of scientific discovery
Qualifications:
Ph.D. in Immunology, Pharmacology or Molecular Biology with a minimum of 6 years post-doctoral experience and with a strong record of innovation and publication.
Immune cell biology expert able to apply skills, theoretical knowledge, and experience to provide scientific direction and approach to projects and challenges.
Minimum of 3 years of industry and/or translational research experience required.
Training in Immunology strongly preferred.
Training in Rheumatology is preferred but not required.
Expertise in multiparameter flow cytometry (spectral).
Excellent interpersonal, verbal, and written communication skills.
Self-motivated, creative, and focused; able to work within a team and to collaborate with colleagues to achieve program goals.
Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.
Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants' needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center (ra-employeehealthsup@its.jnj.com) or contact AskGS to be directed to your accommodation resource.
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