Job Title: Senior Principal Scientist I, Quantitative Pharmacology
Location : Cambridge, MA
About the Job
Are you ready to shape the future of medicine? The race is on to speed up drug discovery and development to find answers for patients and their families. Your skills could be critical in helping our teams accelerate progress.
Sanofi is seeking an experienced Quantitative Pharmacology (QP) project expert to join the Research QP Innovation Group within our Translational Medicine Unit (TMU).
As a member of the QP department, you will represent the Research QP Innovation Group on pre-clinical drug discovery projects, effectively integrating QP science into our strategy of developing first and best in class therapies for Immunology, Inflammation, Oncology, Rare and Neurological diseases.
As an integral project team member supporting early research, you will contribute to the translational strategies for novel modalities, innovative targeting approaches, QP technology applications and transversal scientific initiatives. You will support a breadth of projects, identifying opportunities across the organization to bridge and advance QP sciences with key partner lines to ultimately deliver QP strategic thinking towards the success of the emerging Sanofi portfolio.
We are an innovative global healthcare company with one purpose: to chase the miracles of science to improve people's lives. We're also a company where you can flourish and grow your career, with countless opportunities to explore, make connections with people, and stretch the limits of what you thought was possible. Ready to get started?
Main Responsibilities:
Responsibilities will include but are not limited to:
Characterize the ADME and PK properties for diverse modalities (primarily biotherapeutics)
Conceive and implement the preclinical PKPD strategy for a drug and/or target
Representing QP and the TMU on cross functional project teams as a project team leader
Conceive and implement the strategy towards predicting efficacious and safe human dose levels
Support the QP organization by addressing critical knowledge gaps
About You
Requirements and Qualifications
A Ph.D. in Pharmacokinetics or other relevant field + a minimum of 7 years relevant experience
The ability to function in a matrix and global environment
Experience supporting NBE therapeutics
Ability to drive and lead PK, PKPD and ADME strategies for discovery project teams
Knowledge of and/or ability to conduct non-compartmental analysis (NCA) for non-GLP PK and TK reports
Experience with pharmacokinetics, pharmacometrics, PKPD relationships, bioanalytical techniques and/or ADME principles in a drug discovery setting
Willingness to grow and learn into role
Strong written, presentation and verbal communication skills are essential
Strong leadership and teamwork skills
Preferred Qualifications
Experience with protein engineering concepts
Experience with modeling & simulation concepts
Why Choose Us?
Bring the miracles of science to life alongside a supportive, future-focused team.
Discover endless opportunities to grow your talent and drive your career, whether it's through a promotion or lateral move, at home or internationally.
Enjoy a thoughtful, well-crafted rewards package that recognizes your contribution and amplifies your impact.
Take good care of yourself and your family, with a wide range of health and wellbeing benefits including high-quality healthcare, prevention and wellness programs and at least 14 weeks' gender-neutral parental leave.
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
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Pursue progress , discover extraordinary
Better is out there. Better medications, better outcomes, better science. But progress doesn't happen without people - people from different backgrounds, in different locations, doing different roles, all united by one thing: a desire to make miracles happen. So, let's be those people.
At Sanofi, we provide equal opportunities to all regardless of race, colour, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, ability or gender identity.
Watch our ALL IN video (https://www.youtube.com/watch?v=SkpDBZ-CJKw&t=67s) and check out our Diversity Equity and Inclusion actions at sanofi.com (https://www.sanofi.com/en/our-responsibility/equality-and-inclusiveness) !
US and Puerto Rico Residents Only
Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally inclusive and diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; natural or protective hairstyles; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.
North America Applicants Only
The salary range for this position is:
$147,000.00 - $212,333.33
All compensation will be determined commensurate with demonstrated experience. Employees may be eligible to participate in Company employee benefit programs. Additional benefits information can be found through the LINK (https://benefits.sanofiusallwell.com/fleet/public/index/ba511bf8-5c32-4828-9861-ab985fffab90/?cid=sanofi) .
Global Terms & Conditions and Data Privacy Statement (https://www.sanofi.com/en/careers/global-terms-and-conditions/)
Sanofi is dedicated to supporting people through their health challenges. We are a global biopharmaceutical company focused on human health. We prevent illness with vaccines, provide innovative treatments to fight pain and ease suffering. We stand by the few who suffer from rare diseases and the millions with long-term chronic conditions.
With more than 100,000 people in 100 countries, Sanofi is transforming scientific innovation into healthcare solutions around the globe. Discover more about us visiting www.sanofi.com or via our movie We are Sanofi (https://youtu.be/96EwNjb1TLo)
As an organization, we change the practice of medicine; reinvent the way we work; and enable people to be their best versions in career and life. We are constantly moving and growing, making sure our people grow with us. Our working environment helps us build a dynamic and inclusive workplace operating on trust and respect and allows employees to live the life they want to live.
All in for Diversity, Equity and Inclusion at Sanofi - YouTube (http://www.youtube.com/watch?v=SkpDBZ-CJKw&t=2s)
