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Purification & Analytics Scientist

System One • Boston, MA • 5h ago

Job Title: Purification & Analytics Scientist

Location: Boston, MA

Type: Contract to Hire

Compensation: $84.13

Work Model: Onsite

Hours: Standard business hours

Security Clearance: Not specified

Overview:

Join a growing U.S. biotechnology organization specializing in RNA medicine manufacturing. You'll provide specialist leadership on RNA purification and on the analytical strategy that determines whether a batch can be released.

Responsibilities

Lead specialist in RNA purification and analytical strategy to determine batch release

Manage purification unit operations: tangential flow filtration, membrane or chromatographic purification, including double-stranded RNA removal below 1% w/w and residual DNA below 10 ng/mg

Develop and maintain the product quality attribute list per modality, mapped to quality-control measurement domains

Define analytical target profiles for each attribute according to ICH Q2(R2) and Q14, including accuracy, precision, range, and specificity

Rank and prioritize in-line, at-line, and off-line analytical technologies against established profiles with documented criteria

Requirements

PhD or MS with equivalent experience in analytical chemistry, biochemistry, or bioprocess engineering

Minimum of five years of experience in biologics or nucleic-acid purification and analytical development

Ability to cover both purification process expertise and analytical expertise; candidates strong in only one area will leave a gap

System One, and its subsidiaries including Joulé and Mountain Ltd., are leaders in delivering outsourced services and workforce solutions across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

M3

LI-KM2

Ref: #558-Scientific

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

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