Lead Integration Engineer

System One • Pittsburgh, PA • 3h ago

Title: Lead Integration Engineer

Location: Onsite, Pittsburgh, PA 15213

Type: Direct-Hire/Permanent

Hours: Standard business hours

Overview: Join a cutting-edge lab to discover novel therapeutics that are seeking a highly motivated Lead Engineer to support the integration, optimization, and operation of complex fluidic and instrumentation systems for advanced human-relevant experimental platforms. This role focuses on system-level design and implementation of fluid handling architectures, ensuring reliable, reproducible, and physiologically relevant operation across single- and multi-component platforms. The position will contribute to development of robust, scalable systems that integrate mechanical, fluidic, and control elements to support standardized experimental workflows.

Responsibilities:

Design, develop, and optimize fluidic systems, including manifolds, tubing layouts, and pump-controlled flow networks

Implement stable, leak-free circulation systems with controlled and reproducible flow profiles across experimental platforms

Support development of physiologically relevant flow conditions, including continuous and directional flow regimes

Integrate fluidic systems with broader experimental platforms, including device interfaces, instrumentation, and control systems

Contribute to system-level architecture design, coordinating fluidic, mechanical, and sensing components

Develop and implement control strategies for pumps, valves, and fluid routing systems

Perform system testing, validation, and troubleshooting to ensure operational reliability and consistency

Maintain detailed documentation of system configurations, standard operating procedures (SOPs), and performance validation

Collaborate with multidisciplinary teams to align system functionality with experimental and operational requirements

Contribute to improvement of system robustness, usability, and scalability for sustained and repeatable operation

Requirements:

Bachelor's degree in Mechanical Engineering, Electrical / Systems Engineering, or a related field

Minimum of 3 years of relevant experience in fluid systems, instrumentation, or experimental platform development

Experience with fluid handling systems, pumps, tubing, or flow control architectures

Experience with system integration and hardware-based experimental platforms

Strong analytical, troubleshooting, and problem-solving skills

Ability to work effectively in multidisciplinary research and engineering environments

Preferred Qualifications

Master's or Ph.D. in a relevant engineering discipline

Experience with microfluidics, perfusion systems, or biologically relevant flow systems

Familiarity with control systems, sensors, and automated or semi-automated fluid handling platforms

Experience with design and implementation of complex, multi-component systems

Experience with data acquisition, monitoring systems, or system diagnostics

Experience working at the interface of engineering and biological systems

Experience in controlled or regulated laboratory environments

M3

LI-MD2

Ref: #558-Scientific

System One, and its subsidiaries including Joulé, ALTA IT Services, CM Access, TPGS, and MOUNTAIN, LTD., are leaders in delivering workforce solutions and integrated services across North America. We help clients get work done more efficiently and economically, without compromising quality. System One not only serves as a valued partner for our clients, but we offer eligible full-time employees health and welfare benefits coverage options including medical, dental, vision, spending accounts, life insurance, voluntary plans, as well as participation in a 401(k) plan.

System One is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity, age, national origin, disability, family care or medical leave status, genetic information, veteran status, marital status, or any other characteristic protected by applicable federal, state, or local law.

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