At Lilly, we unite caring with discovery to make life better for people around the world. We are a global healthcare leader headquartered in Indianapolis, Indiana. Our employees around the world work to discover and bring life-changing medicines to those who need them, improve the understanding and management of disease, and give back to our communities through philanthropy and volunteerism. We give our best effort to our work, and we put people first. We're looking for people who are determined to make life better for people around the world.
Overview:
At Lilly, we serve an extraordinary purpose. We make a difference for people around the globe by discovering, developing and delivering medicines that help them live longer, healthier, more active lives. Not only do we deliver breakthrough medications, but you also can count on us to develop creative solutions to support communities through philanthropy and volunteerism.
Orna Therapeutics, Inc., a wholly owned subsidiary of Eli Lilly and Company, is an innovative biotechnology startup based in Watertown, MA, committed to developing groundbreaking therapies for diseases that current approaches cannot address. With our pioneering circular RNA technology, developed at MIT, we are at the forefront of advancing the next generation of RNA therapeutics. Our state-of-the-art expression and delivery platform positions us to tackle complex diseases, including B cell-driven autoimmune disorders, B cell malignancies, sickle cell disease, and beyond.
Position Summary:
We are seeking an exceptional Advisor, Analytical Sciences to join our growing team. In this role, you will partner closely with Platform Science, Discovery, and CMC groups to drive analytical characterization of circular RNA and lipid nanoparticle-based therapeutics with a focus on bioassays. The ideal candidate is a highly motivated scientist who can independently design and execute experiments with rigor, efficiency, and creativity. You will contribute to assay development, method qualification, and product characterization while operating in a fast-paced, collaborative environment.
Responsibilities:
Implement and refine analytical testing strategies for circular RNA and lipid nanoparticle (LNP) formulations.
Develop and optimize drug substance and drug product bio assays; perform in-depth characterization studies for lead candidates and pipeline programs.
Lead method transfer activities to external partners, providing technical oversight, troubleshooting, and ensuring assay robustness and compliance.
Author and review methods, reports, and SOPs to ensure alignment with regulatory expectations.
Generate high-quality data packages; analyze, interpret, and present findings to cross-functional R&D teams.
Foster a positive, innovative, and entrepreneurial team culture; contribute to scientific strategy and continuous improvement initiatives.
Basic Requirements:
PhD, MS, or BS degree in molecular biology, cell biology, biochemistry, or related discipline plus assay development experience and the following years of relevant experience: PhD 0-2 years industry or postdoctoral experience, or MS 7+ years' industry, or BS 10+ years' industry experience.
Experience with various techniques such as FACS, ELISA, Western blotting, nucleic acid sequencing, electrophoresis, and PCR-based methods (RT-qPCR, ddPCR) for quantifying RNA and proteins in complex biological matrices.
Strong proficiency in cell and tissue culture techniques.
Additional Preferences:
Experience in RNA biology or RNA therapeutics is preferred but not required.
Excellent oral and written communication skills, with the ability to clearly present complex data.
Demonstrated ability to thrive in a dynamic, fast-moving research environment with strong problem-solving and interpersonal skills.
Additional Information:
Physical Demands/Travel:
The physical demands of this job are consistent with a lab environment .
Travel:
The physical demands here are representative of those that must be met by an employee to successfully perform the essential functions of this job.
Work Environment:
This position's work environment is in a laboratory environment.
The work environment characteristics described here are representative of those an employee encounters while performing the essential functions of this job.
*To perform this job successfully, an individual must be able to perform the role and responsibilities satisfactorily. The requirements listed above are representative of the knowledge, skill, and/or ability required. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions.
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( https://careers.lilly.com/us/en/workplace-accommodation ) for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia Network, Black Employees at Lilly, Chinese Culture Network, Japanese International Leadership Network (JILN), Lilly India Network, Organization of Latinx at Lilly (OLA), PRIDE (LGBTQ+ Allies), Veterans Leadership Network (VLN), Women's Initiative for Leading at Lilly (WILL), enAble (for people with disabilities). Learn more about all of our groups.
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$138,000 - $202,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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