Master Manufacturing Technician - Upstream

Genentech • Oceanside, CA • 2h ago

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Genentech is the founder of the biotechnology industry and has been delivering on the promise of biotechnology for 50 years. It has been a member of the Roche Group since 2009 and is one of its most important centres of pharmaceutical research. At our company, the patient is at the heart of all R&D efforts, and delivering life-changing therapies to patients while also driving positive change in the global society is the impetus to everything we do.

The position is located in Oceanside, On-site. The schedule could include a rotating (10-12 hour shift), one weekend day, evening or night hours, or full off-shift hours.

The Opportunity

As a Master Manufacturing Technician, you will work within a team to produce and deliver quality products for patients around the world. We are a 24/7 site and the work load is divided across multiple organizations. Technicians are expected to work in a safe manner and follow our Standard Operating Procedures at all times. Doing these two critical aspects of our job helps us maintain our right to operate and commitment to governing bodies around the world.

Our Manufacturing begins in Upstream, where we thaw and scale up our process. Some of the responsibilities for Upstream technicians are: preparing the medium needed for cell growth and maintaining our Cell Cultures which includes the set-up and breakdown of stainless steel bioreactors.

Responsibilities include:

Cell Culture Operations: Manage small-scale cell culture areas by cleaning, setting up, and maintaining 20L batch feed bioreactors. Perform inoculation, spinner seed culture maintenance, cell bank handling, and general seed lab operations including thawing.

Large-Scale Equipment Handling: Operate 120L-15K bioreactors, centrifuges, fixed tanks, and filtration systems. Execute automated CIP (Clean-In-Place) and SIP (Sterilization-In-Place) of fixed equipment.

Solution Preparation & Process Monitoring: Prepare media and solutions for production activities. Monitor and trend process metrics, interpret data to recommend improvements, and use Delta-V automation for production operations.

Troubleshooting and Cross-Functional Collaboration: Independently troubleshoot equipment, investigate complex problems, and implement solutions while coordinating with departments like Engineering, Facilities, and Safety.

Safety, Compliance, and Documentation: Ensure adherence to safety standards, cGMP, SOPs, and manufacturing documentation. Promote a safety-first culture, report incidents, and comply with environmental and safety guidelines.

Who you are:

Minimum Qualifications:

You possess a Bachelor degree with 10 years experience, or Associate degree with 12 years experience, or High School with 14 years experience in a GMP working environment with background in Upstream (Cell Culture)

You are capable of writing technical and detailed reports/summaries

You possess a high level of automation and technical process knowledge as related to prep and bioprocess within area of responsibility

Nice-To-Have Qualifications:

You have a Biotech certificate from approved program.

Physical conditions and PPE requirements:

Ability to work a flexible shift structure

Expected to be on feet for 8 to 10 hours a day.

May climb upwards of 6 flights of stairs a day to maneuver within the manufacturing facility.

Lifting up to 25lbs may be required.

Environment requires that gowning in the form of hospital scrubs, bunny suits, gloves and steel toe boots be worn. Also, no makeup or jewelry can be worn when working in the clean room environment.

May work with hazardous materials and chemicals.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location for this position of Oceanside, CA is $61,600- $90,800. Actual pay will be determined based on experience, level, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

This position also qualifies for the benefits detailed at the link provided below.

Benefits (https://roche.ehr.com/default.ashx?CLASSNAME=splash)

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .

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