Senior Scientist - Bioprocess Development

Insight Global • King Of Prussia, PA • 2h ago

Job Description

One of our large bioprocessing clients is seeking a Senior Scientist to join their R&D team in King of Prussia, PA. This role is fully on site, 5 days/week and will lead downstream process development efforts focused on the chromatographic purification of monoclonal antibodies. This role is central to our clients mission of enabling large and small biopharmaceutical companies to bring transformative therapies to patients faster and more efficiently. This individual will guide a small team (6 reports max) in designing and executing purification strategies that support late-stage development and manufacturing readiness. This role will be 50% hands on bioprocess development and 50% people managing. Some responsibilities include but are not limited to:

Design, execute, and analyze chromatography-based purification processes (Protein A, ion exchange, HIC, etc.) for mAbs.

Develop scalable, robust purification processes tailored to client molecules and manufacturing goals.

Lead technology transfer activities to external manufacturing sites.

Author technical reports, protocols, and support regulatory documentation.

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to HR@insightglobal.com.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: https://insightglobal.com/workforce-privacy-policy/.

Skills and Requirements

M.S. in Biochemistry, Chemical Engineering, Biotechnology, or related field with 8 years of relevant industry experience, or Ph.D. with 5 years of experience in downstream process development for biologics.

Demonstrated expertise in preparative chromatography and antibody purification.

Proven ability to lead small scientific teams and manage lab operations. - Hands-on experience with AKTA systems, Unicorn software, and high-throughout screening platforms (e.g., Tecan Te-Chrom).

Proficiency in analytical techniques such as HPLC, SDS-PAGE, ELISA, UV spectroscopy.

Familiarity with tech transfer, cGMP/cGLP standards, and regulatory documentation.

Experience in client-facing or CDMO environments is a plus.

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