Sr Associate Scientist, Metabolic & Muscle Diseases

Regeneron Pharmaceuticals • Tarrytown, NY • 2h ago

We are seeking a highly motivated and experienced Sr Associate Scientist to join Obesity, Metabolism and Muscle Diseases Group. The individual will serve as a central histological resource, providing expert tissue processing and staining services to multiple Obesity, Metabolism and Muscle Diseases research programs simultaneously. The successful candidate will manage end-to-end histological workflows spanning a broad range of tissue @types, maintain rigorous quality standards. This role demands both deep technical proficiency and strong interpersonal skills to navigate competing program demands and deliver high-quality data on time.

As a Sr Associate Scientist, a typical day may include:

Tissue processing, including tissue fixation, dehydration, clearing, embedding, and sectioning samples from multiple tissue @types (e.g., liver, heart, brain, muscle, adipose).

Routine histological staining (e.g H&E, Sirius Red, PAS, Oil Red O) and special staining according to the program needs

Conduct immunohistochemistry (IHC) and immunofluorescence (IF); develop, optimize, and validate new IHC/IF protocols, antibody titrations, and antigen retrieval conditions.

Apply in situ hybridization (ISH/RNAscope) techniques for gene expression localization where required

Perform image aquation, using different scanning platforms (e.g. Aperio, Zeiss Axioscan), and manage image data repositories

Perform quantitative image analysis using platforms such as HALO, develop and apply customized image analysis algorithms

Generate high-quality figures and data summaries suitable for internal reports, regulatory packages, and peer-reviewed publications.

Maintain and communicate a dynamic workload tracker; proactively flag capacity constraints or scheduling conflicts to stakeholders.

Adapt rapidly to shifting program priorities and animal study schedules.

The candidate will be responsible for maintaining accurate and complete laboratory records.

This role may be for you if:

You enjoy working in a fast-paced environment

You are a fast learner and have desire to expand your skill set and learn new techniques

You are detail oriented, well-organized and can multi-task

You are a team player

You have strong communication skills

To be considered for this role, you must have:

BS with 5+ years or MS with 2+ years of relevant experience

Proficiency in standard and special histochemical staining techniques across multiple tissue @types.

Demonstrated IHC/IF assay development, optimization, and troubleshooting experience

Ability to optimize processing and staining protocols for challenging tissue @types or low-abundance samples

Proficiency with whole-slide imaging systems and digital pathology image analysis software (e.g. HALO)

Experience with in situ hybridization platforms (RNAscope, BaseScope, FISH) is a plus

Strong organizational and record-keeping skills

Ability to manage and prioritize simultaneous requests from multiple stakeholders

Excellent oral and written communication skills

Ability to present data at lab meetings

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/ . For other locations, additional information will be provided during the recruitment process. If you have any questions, please speak with your recruiter.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on-site. Please speak with your recruiter and hiring manager for more information about on-site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$80,300.00 - $131,100.00

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