2026 Summer Intern - Clinical Pharmacology

Genentech • South San Francisco, CA • 2d ago

The Position

Department Summary

Clinical Pharmacology is a dynamic function that plays a critical role in supporting drug development teams and in optimizing the dosing regimen for patients. Utilizing our expertise in pharmacokinetics and pharmacodynamics, Clinical Pharmacologists contribute at every stage of development, applying quantitative pharmacology principles across a molecule's life-cycle for both small molecules, biologics, and novel treatment modalities. The Clinical Pharmacology department is instrumental in shaping future treatments and ensuring they are both safe and effective.

This internship position is located in South San Francisco, on-site.

The Opportunity

The key responsibilities may include, but are not limited to:

Conduct systematic reviews of relevant scientific literature and regulatory documents (e.g., FDA/BLA/NDA submissions) to identify and extract critical information.

Develop, validate, and apply mechanistic Physiologically-Based Pharmacokinetic (PBPK) models, with a particular focus on Physiologically-Based Biopharmaceutics Models (PBBM), to address Clinical Pharmacology questions such as the impact of food, proton pump inhibitors (PPIs), and formulation changes on pharmacokinetics.

Formulate scientifically sound conclusions and present the research outcomes internally and externally.

Program Highlights

Intensive 12-weeks, full-time (40 hours per week) paid internship.

Program start dates are in May/June 2026.

A stipend, based on location, will be provided to help alleviate costs associated with the internship.

Ownership of challenging and impactful business-critical projects.

Work with some of the most talented people in the biotechnology industry.

Who You Are (Required)

Required Education:

You meet one of the following criteria:

Must be pursuing a Master's Degree (enrolled student).

Must have attained a Master's Degree.

Must be pursuing a PhD (enrolled student).

Required Majors: Pharmacokinetics, Pharmaceutics, or other quantitative disciplines (Statistics/Biostatistics, Computational Biology/Chemistry, Chemical/Biomedical Engineering).

Required Skills:

Foundational knowledge and experience in pharmacokinetics and ADME of small molecules.

Experience with PBPK modeling; familiarity with Simcyp and/or MATLAB is strongly preferred.

Preferred Knowledge, Skills, and Qualifications

Excellent communication, collaboration, and interpersonal skills.

Complements our culture and the standards that guide our daily behavior & decisions: Integrity, Courage, and Passion.

Relocation benefits are not available for this job posting.

The expected salary range for this position based on the primary location of California is $50.00 hour. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. This position also qualifies for paid holiday time off benefits.

Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants (https://docs.google.com/forms/d/e/1FAIpQLSdZWlsbfQOvFVIQgHE_iDzWUTlhZvj6FytIzjS7xq6IGh1H5g/viewform) .

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