Scientist - Proteomics

Insight Global • Elwyn, PA • 1w ago

Job Description

The Molecular Modalities Discovery group is seeking a highly motivated scientist with expertise in proteomics and informatics to support capability development in the mass spectrometry (MS)-omics space, with a particular focus on oligonucleotides and single-point mutations. This is a bench-focused role requiring hands-on experience in biological mass spectrometry workflows.

Key Responsibilities

Perform biological mass spectrometry workflows with a primary focus on proteomics.

Support small molecule discovery, including identification and progression of molecules that interact with drug targets.

Execute sample preparation steps, including:

Handling cryogenically preserved cells (not chemically fixed).

Buffer treatment for cell lysis and protein extraction.

Enrichment steps (e.g., amino precipitation).

Protein digestion and peptide processing.

Reconstitution and loading samples onto MS tips for automated analysis.

Learn and apply core workflows for MS-based proteomics.

Collaborate with partners for occasional live-cell handling.

Maintain accurate documentation and adhere to standard operating procedures.

We are a company committed to creating diverse and inclusive environments where people can bring their full, authentic selves to work every day. We are an equal opportunity/affirmative action employer that believes everyone matters. Qualified candidates will receive consideration for employment regardless of their race, color, ethnicity, religion, sex (including pregnancy), sexual orientation, gender identity and expression, marital status, national origin, ancestry, genetic factors, age, disability, protected veteran status, military or uniformed service member status, or any other status or characteristic protected by applicable laws, regulations, and ordinances. If you need assistance and/or a reasonable accommodation due to a disability during the application or recruiting process, please send a request to HR@insightglobal.com.To learn more about how we collect, keep, and process your private information, please review Insight Global's Workforce Privacy Policy: https://insightglobal.com/workforce-privacy-policy/.

Skills and Requirements

Bachelor's degree in Biology, Biochemistry, Chemistry, or related field (advanced degree preferred).

Hands-on experience with mass spectrometry in a biological @context.

Strong understanding of proteomics workflows and sample preparation techniques.

Familiarity with informatics tools for MS data analysis is a plus.

Ability to work independently at the bench and troubleshoot technical challenges. Background in biology and handling biological materials.

Knowledge of oligonucleotide analysis and mutation detection.

Experience with automated MS workflows.

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