Why Mayo Clinic
Mayo Clinic is top-ranked in more specialties than any other care provider according to U.S. News & World Report. As we work together to put the needs of the patient first, we are also dedicated to our employees, investing in competitive compensation and comprehensive benefit plans (https://jobs.mayoclinic.org/benefits/) - to take care of you and your family, now and in the future. And with continuing education and advancement opportunities at every turn, you can build a long, successful career with Mayo Clinic.
Benefits Highlights
Medical: Multiple plan options.
Dental: Delta Dental or reimbursement account for flexible coverage.
Vision: Affordable plan with national network.
Pre-Tax Savings: HSA and FSAs for eligible expenses.
Retirement: Competitive retirement package to secure your future.
Responsibilities
Job Summary
The principal enterprise architect of agentic automation leads the day-to-day operating framework that scales agentic automation across the enterprise. The role transforms strategy into execution by standardizing intake and triage, building guardrails, expanding federated capabilities across DMCs/departments, and stewarding the Citizen Development Program. Success looks like predictable delivery, measurable value (ROI/KPIs), and a continuously improving "push-led" pipeline that advances enterprise goals rather than relying primarily on crowdsourced intake.
Key Responsibilities
Leadership & Strategy
Operate the Agentic Operations & Enablement function that underpins the Enterprise Automation program.
Translate enterprise automation and agentic strategy into standard processes, playbooks, and delivery cadences.
Drive a push-oriented pipeline aligned to business objectives and ROI; supplement with high-quality pull intake when appropriate.
Stay current on RPA, LLMs, and agentic orchestration trends to inform roadmaps and operating methods.
Program Development
Define program KPIs and balanced scorecards (e.g., cycle time, accuracy, adoption, deflection, cost savings, risk reduction, satisfaction).
Build value models and ROI calculators for agentic use cases; maintain benefit realization tracking post-go-live.
Standardize and optimize operating practices across the portfolio (intake ? triage ? discovery ? design ? build ? test ? deploy ? run).
Establish and maintain controls and guardrails for security, compliance, data access, and safe use of autonomous/semi-autonomous agents.
Grow and support federated automation teams across DMCs/departments with shared standards, reusable components, and coaching.
Expand and steward the Citizen Development Program with curricula, certification paths, governance tiers, and reusable "agent patterns."
Advocacy & Education
Advocate for RPA/AI/agentic solutions through enablement briefings, roadshows, and community forums.
Lead top-down (executive- and service-line-driven) and bottoms-up (frontline- and citizen-led) ideation streams, curating into a single prioritized pipeline.
Build trust and credibility with internal and external stakeholders (vendors, ecosystem partners, advisory groups) to accelerate safe, scalable adoption.
Team & Relationship Management
Lead a small cross-functional team (analysts, coordinators, federated contributors) to identify and qualify automation opportunities.
Provide mentorship on process assessment, agentic design patterns, documentation quality, and delivery best practices.
Manage iterative stakeholder engagement: schedule and run ideation sessions, discovery workshops, and executive updates.
Conduct high-level process assessments to generate pipeline and perform use-case evaluations with clear acceptance criteria.
Program Coordination & Delivery
Coordinate with Automation Hub leadership on portfolio progress, dependencies, and risk/issue management.
Oversee administrative facets: vendor relationships, SOW coordination, licensing inventories, budget tracking, and resource plans.
Create detailed project plans, RAID logs, and milestone trackers; maintain dashboards for status, risks, KPIs, and value realization.
Measure project performance with appropriate tools and techniques; publish recurring reports and escalate issues with actionable options.
Qualifications
Qualifications
Experience: 5-8 years in automation operations, business process management, digital transformation, or PMO/enablement roles.
Technical Acumen: Familiarity with RPA platforms (e.g., UiPath/Power Automate), LLM-driven/agentic orchestration concepts, and enterprise integration basics.
Operational Excellence: Proven ability to standardize processes, manage intake/triage, and run measurement/benefits realization.
Stakeholder Skills: Strong communication, facilitation, and relationship management across clinical/operational/IT stakeholders and vendor partners.
Governance Mindset: Comfort with controls, compliance, and change management for autonomous/semi-autonomous systems.
Education & Experience
Bachelor's degree in Information Systems, Computer Science, Industrial Engineering, Business, or related field; master's preferred.
Demonstrated experience building or scaling an automation enablement function, PMO, or citizen development program.
Portfolio evidence of KPI design, ROI modeling, and value tracking for automation initiatives.
Competencies
Agentic Literacy: Understand when to apply autonomous vs. human-in-the-loop patterns and how to design guardrails.
Program Rigor: Habit of codifying standards, templates, and reusable assets for predictable outcomes.
Value Orientation: Bias toward measurable results, transparent metrics, and credible storytelling of impact.
Change Leadership: Able to coach teams, reduce friction, and grow confidence in working with digital agents.
Exemption Status
Exempt
Compensation Detail
Education, experience and tenure may be considered along with internal equity when job offers are extended.
Benefits Eligible
Yes
Hours/Pay Period
80/pay period
International Assignment
No
Site Description
Just as our reputation has spread beyond our Minnesota roots, so have our locations. Today, our employees are located at our three major campuses in Phoenix/Scottsdale, Arizona, Jacksonville, Florida, Rochester, Minnesota, and at Mayo Clinic Health System campuses throughout Midwestern communities, and at our international locations. Each Mayo Clinic location is a special place where our employees thrive in both their work and personal lives. Learn more about what each unique Mayo Clinic campus has to offer, and where your best fit is. (https://jobs.mayoclinic.org/alllocations)
Equal Opportunity
All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, gender identity, sexual orientation, national origin, protected veteran status or disability status. Learn more about the "EOE is the Law" (https://www.eeoc.gov/poster) . Mayo Clinic participates in E-Verify (https://www.e-verify.gov/sites/default/files/everify/posters/EVerifyParticipationPoster.pdf) and may provide the Social Security Administration and, if necessary, the Department of Homeland Security with information from each new employee's Form I-9 to confirm work authorization.
Recruiter
Adriana Semko
Equal opportunity
As an Affirmative Action and Equal Opportunity Employer Mayo Clinic is committed to creating an inclusive environment that values the diversity of its employees and does not discriminate against any employee or candidate. Women, minorities, veterans, people from the LGBTQ communities and people with disabilities are strongly encouraged to apply to join our teams. Reasonable accommodations to access job openings or to apply for a job are available.
