We're here for one reason and one reason only - to cure cancer. Every moment is dedicated to developing treatments and every action moves us one step closer to our goal. We've made incredible scientific breakthroughs and our pioneering personalized CAR T-cell therapies have changed the paradigm. But we're not finished yet.
Join Kite, as we make even bigger advances in cancer therapies, and help shape where our business and medical science goes next.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Kite and help create more tomorrows.
Job Description
Scientist, Cell Biology -CAR T Cell Enhancement Development
Kite Pharma is the leader in chimeric antigen receptor (CAR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Their goal is to provide rapid, long-term durable response and eliminating the burden of chronic diseases. Kite Pharma's Cell Therapy Research division is seeking a Research Scientist to join the CAR T cell enhancement team to lead studies that develop and evaluate strategies to improve CAR T cell functions and safety in solid and hematological tumors.
Responsibilities
Independently design, plan, and effectively execute experiments based on strategy, project timelines and goals perform experiments
Conduct cell-based functional and biochemical assays to select lead CAR T candidates for clinical development of next generation CAR-T cell products
Conduct genetic/biochemical manipulation of T cells and evaluate impact on T cell function in vitro and in vivo
Analyze, organize, and communicate results at different research and cross-functional meetings
Document experimental results to enable clinical studies and patent applications
Work effectively with other functions (including Process Development, Translational Medicine, Clinical Development) to ensure alignment cross-functionally
May serve as a core team member or leader on a project team
Coordinate tasks across multiple projects, demonstrating prioritization and planning
May mentor junior team members and supervise the work of a research team including, but not limited to, organizing and prioritizing laboratory work and review of generated experimental results
Basic Qualifications
Advanced scientific degree (i.e. MD, PharmD, PhD)
OR
Master's Degree and 4+ years of scientific experience
OR
Bachelor's Degree and 6+ years of scientific experience
Preferred Qualifications
Strong background in cancer immunotherapy, immunology, and/or gene therapy
Experience working with engineered T cells and/or other immune cell @types (i.e., NK cells, myeloid cells, etc.)
Direct experience in cell engineering using viral or non-viral methods or gene editing
Understanding of protein engineering and synthetic biology principles applied to cell therapy
Demonstrated independence in experimental design, data analysis, interpretation, and presentation
Experience in T-cell functional characterization assays including in vitro cytotoxicity, proliferation, cytokine/chemokine measurements, cell signaling, activation, differentiation, and exhaustion
Proficient in cell culture aseptic technique
Proficient in multi-parameter flow cytometry (panel design, sample acquisition, data processing) and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel)
Experience in molecular and cellular biology techniques, including by not limited to: PCR, qPCR, cloning and Western blot
Maintain a high degree of accuracy and attention to detail; strong organizational and record keeping skills
Comfortable in a flexible and fast-paced company environment with minimal direction and able to adjust workload based upon changing priorities
Strong collaboration, excellent interpersonal and communication skills
Experience using both written and verbal communication, including presentations, to communicate results to a diverse cross-functional audience
Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description
The position is based in Foster City, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .
The salary range for this position is: $146,540.00 - $189,640.00. Kite considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
https://www.gilead.com/careers/compensation-benefits-and-wellbeing
Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
Kite is a biopharmaceutical company engaged in the development of innovative cancer immunotherapies with a goal of providing rapid, long-term durable response and eliminating the burden of chronic care. The company is focused on chimeric antigen receptor (CAR) and T cell receptor (TCR) engineered cell therapies designed to empower the immune system's ability to recognize and kill tumors. Kite is based in Santa Monica, CA. For more information on Kite, please visit www.kitepharma.com . Sign up to follow @KitePharma on Twitter at www.twitter.com/kitepharma .
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Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' (https://www.eeoc.gov/employers/eeo-law-poster) poster.
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Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Kite Pharma Employees and Contractors:
Please apply via the Internal Career Opportunities portal in Workday.
Change The World With Us
Everyone at Kite is grounded by one common goal - curing cancer. Every day, we aim to establish a direct line between that purpose and our day-to-day work.
We are creating Kite together, with the recognition that the best teams are built by the best people. We maintain an attitude of curiosity, and creativity with each challenge as we develop a new market for cancer therapies. We appreciate and respect one another, and most importantly, we don't take success for granted.
While we've come a long way to make what others viewed as impossible, possible, we know one thing is certain. Today is just the beginning.
